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"AcquisitionMetadata_Ridge100", "retained": 0.0, "recall": 0.0, "lower95": 0.0, "upper95": 0.09090909090909091 }, { "model": "AcquisitionMetadata_HGB100", "retained": 1.0, "recall": 0.09090909090909091, "lower95": 0.0, "upper95": 0.2727272727272727 } ], "context": "OASIS primary human hepatocytes; independently held-out compounds", "unit": "held-out compound", "lossDefinition": "Signed metabolic loss relative to same-plate DMSO, averaged over eight concentrations after frozen well/source aggregation.", "uncertainty": "Comparison recall intervals: deposited 95% percentile intervals from 2,000 compound-bootstrap samples.", "interpretation": "Retention of strongly metabolically injurious compounds at a fixed 5% selection budget. This use-specific analysis is distinct from broad response-fidelity classification.", "inputContext": "Released 768-feature brightfield-channel DINO representation from fixed, stained acquisitions; fluorescence-derived cell counts are separate diagnostic comparator inputs.", "sources": [ "paper/figure_sources/final/figure6/source_data/external_use/figure_source_data.tsv", "paper/figure_sources/final/figure6/source_data/external_use/external_hit_membership.csv", "paper/figure_sources/final/figure6/source_data/external_use/external_selection_boundaries.csv" ] } }